Mixed effect estimation in deep compartment models
Journal of Pharmacokinetics and Pharmacodynamics https://doi.org/10.1007/s10928-024-09931-w
Value-Based Integrated Care
Int J Health Policy Manag 2024;13:8038 https://doi.org/10.34172/ijhpm.2024.8038
Peri-operative desmopressin
Haemophilia. 2024;1–12 DOI:10.1111/hae.14946
LSD1/KDM1A and GFI1B repress endothelial fate
Vol. 109 No. 12 (2024): December, 2024 https://doi.org/10.3324/haematol.2024.285214
Pharmacokinetic–Pharmacodynamic Modelling in Hemophilia A
European Journal of Drug Metabolism and Pharmacokinetics (2024) 49:191–205 https://doi.org/10.1007/s13318-024-00876-6
ETV6R369W disrupts megakaryopoiesis in a dominant negative manner
On the 23rd of January, we presented our recent work about the transcription factor ETV6 related inherited thrombocytopenia at the Dutch Hematology Congress. In this new study, we confirmed the dominant negative function of the missense ETV6 variant, ETV6R369W, in megakaryocyte and platelet generation. Our findings contribute to the understanding [...]
PhD defense Alexander Janssen
On the 23rd of January 2025 Alexander Janssen, PhD WP06, defended his thesis "Artificial Intelligence for intelligent care. How machine learning algorithms can enchance the personalised treatment of patients with haemophilia A". If you missed the PhD defense you can watch it now (this video is in Dutch) using [...]
A Generative and Causal Pharmacokinetic Model for Factor VIII in Hemophilia
CLINICAL PHARMACOLOGY & THERAPEUTICS | VOLUME 0 NUMBER 0 | Month 2024 doi:10.1002/cpt.3203
PBPK modeling of recombinant factor IX Fc fusion protein
CPT Pharmacometrics Syst Pharmacol. 2024;13:1630–1640 Lees hier
PhD defense Michael Cloesmeijer
On the 18th of December 2024 Michael Cloesmeijer, PhD WP06, defended his thesis "The dynamics of pharmacometrics to personalize the treatment of inborn bleeding disorders". If you missed the PhD defence you can watch it now (this video is in Dutch) by clickin HERE. To read the thesis you [...]